Retatrutide 20mg — Triple Receptor Agonist | Nexus Lab
Weight Management · Triple Agonist

Retatrutide

Triple Receptor Agonist — GLP-1 / GIP / Glucagon

20mg / Vial
≥99% Purity
HPLC Verified
Lot Traceable
4.9/5 — based on 128 lab reviews
Limited batch — 14 vials left at this lot price
Secure Checkout
Discreet Packaging
COA With Every Lot
Shipping & Handling
Ships within 1–2 business days in insulated, temperature-aware packaging. Tracking sent by email.
Certificate of Analysis
Every lot ships with a downloadable HPLC/MS Certificate of Analysis confirming purity and identity.
Research Use Only
This product is sold strictly for laboratory research. Not for human consumption, diagnostic, or therapeutic use.
Mechanism of Action

Three Pathways. One Molecule.

Retatrutide's defining property is the simultaneous activation of three distinct endocrine receptors — enabling research into appetite, energy expenditure, and nutrient partitioning within a single compound.

01 — GLP-1

Satiety Signaling

Enhances satiety signaling and modulates gastric emptying, supporting reduced caloric intake models.

02 — GIP

Incretin Response

Participates in incretin signaling and the handling of glucose and lipids at the cellular level.

03 — Glucagon

Energy Expenditure

Contributes to energy expenditure and mobilization of fat stores, with central effects on hunger circuits and food reward.

Research Findings

Observed Outcomes in Research Models

Documented effects across obesity, insulin resistance, and body composition research applications.

Reduced Appetite & Caloric Intake

Marked reduction in appetite and caloric intake observed across research models.

Improved Metabolic Efficiency

Enhanced glucose regulation and metabolic efficiency documented in controlled studies.

Increased Energy Expenditure

Elevated energy expenditure and lipid oxidation, supporting body recomposition research.

Visceral Fat & Body Composition

Applications in obesity, insulin resistance, and body composition research models.

Vial Preparation Overview

Reconstitution — General Overview

For research reference only. Final protocol should be determined by the researcher.

1

Start

Lyophilized peptide powder, sealed vial.

2

Add Diluent

Add sterile bacteriostatic water slowly down the vial wall.

3

Gentle Swirl

Swirl gently until powder is fully dissolved. Never shake.

4

Solution

Clear solution is ready for laboratory use.

5

Store

Refrigerate reconstituted solution at 2–8°C.

⚠ Do not shake. Avoid vigorous agitation to preserve peptide integrity.

Handling Considerations

  • Use aseptic technique at all times
  • Use sterile laboratory-grade water for reconstitution
  • Do not shake the vial — gently swirl only
  • Avoid repeated freeze-thaw cycles
  • Store reconstituted solution under refrigeration
  • Use calibrated laboratory equipment for accuracy

Concentration Reference

PeptideDiluentApprox. Conc.
20mg1 mL20 mg/mL
20mg2 mL10 mg/mL
20mg3 mL6.67 mg/mL
20mg5 mL4 mg/mL

For research reference only. Final concentration should be determined by the researcher based on their protocol.

≥99% Purity

HPLC-verified synthesis on every batch

Lot Traceability

Full documentation per production lot

Multi-Stage QC

International laboratory quality standards

Secure Checkout

Your research order is processed safely

From The Field

Trusted By Research Teams

★★★★★

"Consistent purity across every lot we've tested. Documentation makes it easy to keep our protocols audit-ready."

A.M.
Dr. A. MoralesIndependent Research Lab
★★★★★

"Retatrutide from Nexus Lab has been the most reliable triple-agonist compound we've sourced for metabolic studies."

R.C.
Research CoordinatorBioPerformance Institute
★★★★★

"Fast dispatch, discreet packaging, and a COA that matches the label every time. Exactly what serious research requires."

L.C.
L. ChenLongevity Research Group
Common Questions

Frequently Asked Questions

What is Retatrutide used for in research?

Retatrutide is studied as a triple GLP-1/GIP/glucagon receptor agonist in models of obesity, insulin resistance, energy expenditure, and body composition.

Is this product intended for human use?

No. This peptide is sold strictly for laboratory research use. It is not for human consumption, diagnostic, or therapeutic use.

How should the vial be stored?

Store the lyophilized powder at −20°C. Once reconstituted, keep the solution refrigerated at 2–8°C, protected from light, and avoid freeze-thaw cycles.

What diluent volume should I use?

See the concentration reference table above. The final volume depends on your specific research protocol and desired concentration.

Does each order include a Certificate of Analysis?

Yes. Every lot ships with an HPLC/MS-verified Certificate of Analysis confirming ≥99% purity and identity.

Research Use Only (RUO). This product is not a drug, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease. Not for human or animal consumption. By purchasing, you confirm you are a qualified researcher acquiring this product for laboratory research purposes only.

Ready to add Retatrutide to your research protocol?

≥99% purity, lot-traceable, HPLC-verified — with a Certificate of Analysis in every shipment.